منابع مشابه
Mind the Organelle Gap - Peroxisome Contact Sites in Disease.
The eukaryotic cell is organized as a complex grid system where membrane-bound cellular compartments, organelles, must be localized to the right place at the right time. One way to facilitate correct organelle localization and organelle cooperation is through membrane contact sites, areas of close proximity between two organelles that are bridged by protein/lipid complexes. It is now clear that...
متن کاملAthPEX10, a nuclear gene essential for peroxisome and storage organelle formation during Arabidopsis embryogenesis.
In yeasts and mammals, PEX10 encodes an integral membrane protein with a C3HC4 RING finger motif in its C-terminal domain and is required for peroxisome biogenesis and matrix protein import. In humans, its dysfunction in peroxisome biogenesis leads to severe Zellweger Syndrome and infantile Refsum disease. Here we show that dysfunction of a homologous gene in Arabidopsis leads to lethality at t...
متن کاملMembrane elongation factors in organelle maintenance: the case of peroxisome proliferation.
Separation of metabolic pathways in organelles is critical for eukaryotic life. Accordingly, the number, morphology and function of organelles have to be maintained through processes linked with membrane remodeling events. Despite their acknowledged significance and intense study many questions remain about the molecular mechanisms by which organellar membranes proliferate. Here, using the exam...
متن کاملDioscorea Plants: A Genus Rich in Vital Nutrapharmaceuticals- A Review
Dioscorea species, known as “Yams,” belong to family Dioscoreaceae. This genus consists ofmore than 600 species distributed from Africa, Asia, the Caribbean’s South America, and theSouth Pacific islands. Their organoleptic properties make them the most widely used carbohydratefood and dietary supplements. The underground and/or aerial tubers represent valuable sources...
متن کاملThe incredible shrinking organelle.
considering its central role in energy metabolism in almost all eukaryotes, the mitochondrion is an amazingly plastic organelle, both evolutionarily and functionally. the few genes that the mitochondrial genome (mito chondrial DNa; mtDNa) encodes are clearly bacterial in origin —emanating from the α-proteobacterial lineage—supporting the widely held view that the mitochondrion is the evolutiona...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1996
ISSN: 0014-5793
DOI: 10.1016/s0014-5793(96)90661-4